NBME Nursing Study guides, Class notes & Summaries

Stent contain paclitaxel. this drug decrease incidence of restenosis by ? prevention of SM growth over the stent microtubules spindle inhibitors function ? growth inhibitor decrease DHT & 5-a reductase indicates hypoplasia of which organ ? prostate Fibromuscular dysplasia, periumbilical bruit, angiography shows? beaded stenosis of renal artery Fibromuscular dysplasia presents with ? String of beads on renal artery Pectus Excvatum (marfan syndrome), what murmur the patient most likely w...

acute kidney injury acute reduction in GFR -GFR represents the sum of the filtration rate -therefore, GFR reflects functioning renal mass RFs -HTN, CKD, dehydration complications -hyperkalemia -metabolic acidosis -CKD AKI -- prerenal decreased renal perfusion hemorrhage, congestive heart failure, diuretic use osmolality > 500 FeNa+ < 1% Na+ < 20 BUN/Cr > 20:1 AKI -- intrarenal acute tubular necrosis -ischemia and toxic causes osmolality < 350 FeNa+ > 2% Na...

1. Patient had anaphylaxis following the transfusion of fresh frozen plasma. What is the genetic deficiency? IgA deficiency. Patient with this disease may have preformed antibodies against IgA 2. How does sitagliptin work? It is a competitive inhibitor of dipeptidyl peptidase-4 (DPP4). It prevents breakdown of GI incretins (ex: glucagon-like peptide, GLP-1) and promote endogenous release of insulin. ** DPP4 inhibitor increases endogenous insulin 3. What are acoustic neuromas? Vestibula...

A 2 year old girl who is exposed to the sun has progressive development of dryness of the skin, excessive freckling, and keratoses. Skin fibroblasts cultured from this child are most likely to be defective in which of the following? Nuclear excision repair of pyrimidine dimers a 65 year old man has a radical prostacetomy and lymph node dissection for adenocarcinoma of the prostate. which of the following features is involved in the grading of this neoplasm Tumor size A man with a fair ...

Wide pulse pressure and bounding peripheral pulses - PDA Echo findings in dilated cardiomyopathy - Diffuse hypokalemia and dilation of the ventricles Causes of dilated cardiomyopathy - Viral illness, alcohol, ischemia Tx for life threatening hyperkalemia - Calcium chloride or calcium gluconate X-ray finding doe ankylosing spondylitis - Narrowing or sclerosis of the SI joints Cause of amenorrhea is bleeding occurs after progesterone challenge - Anovulation Treatment for SIADH - Fluid restri...

Mitotic cyclin synthesis G2 phase Vitamin E def anemia Hemolytic anemia~ red antioxidants vs B12 def (megaloblastic macrocytic anemia) Hemolysis~ dec Hgb/hematocrit, inc LDH (normal MCV), and neurologic symptoms vs B12 def: dec Hgb/hematocrit, inc MCV, and neurologic symptoms (dorsal column) Volume of distribution Vd = (amount of drug in the body) / (plasma drug concentration) Achondroplasia Endochondrial ossification dysfunction (inhibit chondrocyte proliferation) TGF beta over expres...

Formation of hypnozoites -Pt has malaria → one of the features is that it forms hypnozoites and has the PBS shown Chloroquine resistance -Can happen but it is not a feature A 30M, who is a migrant farm worker presents to the ED b/c of a 1-wk Hx of fever, chills, & severe headache. He immigrated to the midwestern USA from Honduras 1 year ago. He is alert. Temp is 104F, pulse is 101/min, RR are 20/min, BP is 105/62. The lungs are clear to auscultation. Cardiac exam is normal. The abd i...

Chronic inflammatory disease of spine and sacroiliac joints, uveitis, aortic regurge - ***Ankylosing spondylitis imaging of uterus shows "snow storm" - ***hydatidiform mole what atypical cells are seen in EBV - ***CD 8 T cells subacute combined degeneration (degeneration of dorsal columns, lateral corticospinal tracts, and spinocerebellar tracts) without megaloblastic anemia - ***Vitamin E def this bug is clinically detected by presence of antigen in the urine - ***legionella pneumophi...

What are sentinel lymph nodes? First group of lymph nodes draining a specific organ Describe the lymph node drainage of the GI tract *Trachea and esophagus => Mediastinal *Liver, spleen, pancreas, stomach, upper duodenum => Celiac *Lower duodenum, jejunum, ilecum, colon to splenic flexure => SMA *Colon from splenic flexure to upper rectum => IMA *Lower rectum to anal canal (above pectinate line) =>Internal Iliac Anal rectum (below pectinate line) =>Superficial inguinal ...

TRYPTASE MAST CELL TRYPSIN PANCREAS - ***Tryptase Mast Cell Specific marker mast cell activation type 1 hypersensitvity uriticaria angioedema visceral edema hypotension Length Constant = Myelination - ***Demylination in MS Decreases Length Constant A-Delta Fibers thin myelinated fibers - ***Thin Myelinated Nerve Fibers Detect Temperature + Nociceptive GTO 1B extrafusal fibers - ***Series Connection Increase Tension transmit via GTO 1b contact inhibitory interneuron Prevents damage ...