Glucose Homeostatis and the Pathogenesis of Diabetes Mellitus notes

Mr. X, age 57, presented to his physician with marked fatigue, nausea with occasional diarrhea,and a sore, swollen tongue. Lately, he also has been experiencing a tingling feeling in his toesand a feeling of clumsiness. Microscopic examination of a blood sample indicated a reducednumber of erythrocytes, many of which are megaloblasts, and a reduced number of leukocytes,including many large, hypersegmented cells. Hemoglobin and serum levels of vitamin B12 werebelow normal. Additional tests confir...

Mr. X, age 57, presented to his physician with marked fatigue, nausea with occasional diarrhea,and a sore, swollen tongue. Lately, he also has been experiencing a tingling feeling in his toesand a feeling of clumsiness. Microscopic examination of a blood sample indicated a reducednumber of erythrocytes, many of which are megaloblasts, and a reduced number of leukocytes,including many large, hypersegmented cells. Hemoglobin and serum levels of vitamin B12 werebelow normal. Additional tests confir...